Bone Marrow Transplant in Delhi

A bone marrow transplant (BMT), also called bone marrow transplantation, is a specialised procedure that replaces diseased or damaged marrow with healthy stem cells. These new cells help restore normal blood production and strengthen the immune system.
BMT is often recommended for leukaemia, lymphoma, aplastic anaemia, thalassemia, immune disorders, and various bone marrow failure syndromes.

Under Dr. Satyendra Katewa, a leading expert in bone marrow transplant in Delhi, patients receive safe, evidence-based care. His team manages the bone marrow donor process, ensuring proper matching for matched sibling, unrelated, and haploidentical donors, while guiding families about sibling donor bone marrow transplant risks and long-term care.

What Is a Bone Marrow Transplant and How Does It Work

A BMT replaces faulty stem cells with healthy ones. These stem cells begin producing normal blood cells and gradually rebuild the immune system.

Types of Bone Marrow Transplants

Matched Sibling Donor (MSD):
Fully matched brother or sister, usually the best option.

Matched Unrelated Donor (MUD):
Volunteer donor from national or international registries.

Haploidentical Transplant:
Half-matched donor (typically a parent) when a full match isn’t available.

Autologous Transplant:
Uses the patient’s own stem cells, mainly for certain lymphomas and myeloma.

When Is Bone Marrow Transplant Recommended?

A BMT is considered when bone marrow is unable to produce healthy blood cells or when replacing diseased stem cells offers the best chance of long-term cure.

It is commonly recommended for:

• Acute and chronic leukemia
• High-risk or relapsed lymphoma
• Aplastic anemia
• Thalassemia, sickle cell disease
• Genetic or acquired marrow failure syndromes
• Relapsed or treatment-resistant blood cancers

How BMT Supports Treatment

BMT may be used:

• After chemotherapy to restore healthy marrow
• As curative therapy for high-risk cancers
• To rebuild a severely weak immune system

Special Indications in Children

Children with leukaemia, thalassemia major, immune deficiencies, and genetic disorders often benefit from timely BMT. Dr. Katewa provides specialised pediatric care with safe conditioning, precise donor selection, and intensive monitoring.

Diagnostic Tests Before Bone Marrow Transplant in Delhi

A detailed pre-transplant evaluation ensures safety, correct donor selection, and accurate transplant planning.

Tests Performed at Dr. Katewa’s Centre

Blood Tests:
CBC, liver/kidney function, viral screening, and immune profile.

Bone Marrow Evaluation:
Aspiration and biopsy to assess disease activity.

Imaging Studies:
CT, MRI, PET-CT, or ultrasound to check organ function and disease spread.

Genetic & Molecular Testing:
Identifies mutations and risk categories for personalised transplant planning.

HLA Typing:
Matching for sibling, unrelated, or haploidentical donors.

Heart & Lung Function:
Echocardiography, ECG, and PFTs to assess fitness for conditioning therapy.

Infection Screening:
Includes HIV, hepatitis, CMV, and other treatable infections.

This comprehensive evaluation ensures a safe, effective, and personalised BMT treatment plan in Delhi.

Step-by-Step Bone Marrow Transplant (BMT) Procedure in Delhi

A bone marrow transplant (BMT) is performed in carefully planned phases to ensure maximum safety and long-term success. The entire process, from preparation to recovery, takes several weeks to months, depending on the patient’s health and the type of transplant.

1. Pre-Transplant Conditioning (Preparation Phase)

The first step is called conditioning therapy, where high-dose chemotherapy ± radiation is used to:

• Clear diseased marrow
• Destroy cancer cells
• Create space for new stem cells
• Suppress immunity to prevent rejection

The type and intensity of conditioning depend on the disease, age, and overall health.

Types of Conditioning

• Myeloablative regimen: Strong chemotherapy; used for leukaemia/lymphoma with high cure intent
• Reduced-intensity regimen: Milder; preferred for older or weaker patients
• Non-myeloablative regimen: Very low-intensity; often used in high-risk cases needing gentler therapy

1. Stem Cell Collection (Donor or Patient)

Stem cells are collected before the transplant, depending on the type:

For Donor Transplants (MSD/MUD/Haploidentical)

• The donor receives injections to increase the stem cell count
• Stem cells collected from the blood using a machine (apheresis)
• Sometimes collected directly from bone marrow under anaesthesia

For Autologous Transplants

• Patient’s own stem cells are collected after priming
• Frozen and stored until the transplant day

This step forms the core of the bone marrow donor process.

1. Transplant Day (Stem Cell Infusion)

Often called Day 0, this is the central part of the bone marrow transplant procedure.

• Healthy stem cells are infused into the vein through a central line
• The process is painless and similar to a blood transfusion
• No anaesthesia is needed

After infusion, the new stem cells travel to the bone marrow and begin rebuilding the blood and immune systems.

1. Engraftment Phase (Recovery Inside the Hospital)

This is the most crucial stage and requires strict infection control.

During Engraftment

• New cells begin producing white cells, red cells, and platelets.
• This usually starts between Day +10 and Day +28
• Patients are kept in a protected BMT unit to prevent infections.

Daily Monitoring Includes:

• CBC and kidney/liver function tests
• Infection surveillance
• Symptoms check (fever, rashes, mouth sores)
• Management of nausea, mucositis, weakness, and immunosuppression

Doctors closely monitor for early complications such as infection or graft-versus-host disease (GVHD).

1. Discharge & Early Home Recovery

Patients are discharged once:

• Engraftment is stable
• Infections are controlled
• Eating and hydration are normal

Early Recovery Requires:

• Regular follow-up visits (often twice a week initially)
• Clean home environment
• Avoiding crowds, travel, and outside food
• Taking preventive antibiotics, antivirals, and antifungals

Families are counselled on BMT recovery time, which varies from 3 to 12 months.

1. Long-Term Recovery & Immune Rebuilding

The immune system can take 6–12 months to recover fully.

Focus areas include:

• Nutrition and hydration
• Preventing infections
• Gradually resuming work/school
• Vaccination schedule after 6–12 months
• Monitoring for late effects

Dr. Katewa’s team provides continuous support, counselling, and monitoring through every phase.

Hospital Stay During Bone Marrow Transplant

A typical BMT hospital stay in Delhi lasts 3–6 weeks, depending on:

• Type of transplant (MSD/MUD/haplo)
• Conditioning intensity
• Infection status
• Engraftment speed

Special HEPA-filtered BMT rooms reduce infection risk and improve outcomes.

Key Benefits of Bone Marrow Transplant

A successful BMT can:

• Cure many high-risk blood cancers
• Restore normal blood production
• Improve long-term survival
• Treat genetic blood disorders such as thalassemia
• Rebuild the immune system in severe immune deficiencies

Modern BMT techniques have made the procedure safer, with faster recovery and reduced complications.

Recovery and Post-Transplant Care

Recovery is a gradual process and focuses on rebuilding strength and immunity.

Diet & Nutrition

• High-protein meals (dal, paneer, eggs, lean meat)
• Freshly cooked food only
• No raw salads or street food
• Hydration: 2–2.5 litres/day

Infection Prevention

• Mask use in public
• Frequent handwashing
• Avoiding sick contacts
• Maintaining room hygiene

Managing Side Effects

Temporary effects may include:

• Fatigue
• Appetite loss
• Weak immunity
• Skin rashes
• Mouth sores

Supportive care helps ease symptoms and improve comfort.

Emotional & Mental Support

Psychologists and counsellors help patients handle stress, anxiety, and emotional changes, especially during long treatments.

Follow-ups

Regular follow-up tracks:

• Blood counts
• Organ health
• GVHD signs
• Immune recovery

Bone Marrow Transplant Cost in Delhi

The bone marrow transplant cost in Delhi generally ranges from ₹10,00,000 to ₹25,00,000, depending on:

• Type of transplant (MSD, MUD, haploidentical, autologous)
• Hospital facilities
• Conditioning regimen
• Donor testing & stem cell processing
• Duration of hospital stay
• Additional supportive care

For international patients, costs may vary depending on the hospital category and procedural requirements.

Why Choose Dr. Satyendra Katewa for Bone Marrow Transplant

• Extensive Experience: Expert in pediatric & adult BMT

• Advanced Infrastructure: HEPA-filtered BMT units

• Safe Donor Process: Accurate HLA matching and donor counselling

• Personalised Care: Treatment plans based on genetic & molecular testing

• Holistic Support: Nutrition, psychological care, and long-term monitoring

• Strong Outcomes: High success rates across leukaemia, lymphoma, aplastic anaemia, sickle cell disease, and thalassemia

Patients benefit from a compassionate, transparent, and evidence-based approach.

Book an Appointment for Bone Marrow Transplant (BMT) in Delhi

If you or your loved one is advised to undergo a bone marrow transplant, consult Dr. Satyendra Katewa for safe, evidence-based, and personalised BMT treatment in Delhi.
During your consultation, you will receive:

• A complete evaluation of your condition
• Guidance on donor selection and transplant planning
• Clear counselling on risks, benefits, and expected recovery
• Transparent discussion of bone marrow transplant cost in Delhi

Book your appointment to understand the right treatment pathway and begin a supported journey toward recovery.

International Patients – Bone Marrow Transplant in India

Dr. Satyendra Katewa welcomes international patients seeking affordable, high-quality bone marrow transplantation in India.
His dedicated international care team assists with:

• Medical visa support and documentation
• Airport pickup and accommodation planning
• Donor matching coordination & HLA typing
• Clear cost estimates for BMT treatment
• Post-transplant monitoring through teleconsultation

Patients trust Dr. Katewa for his experience, transparent approach, and strong transplant outcomes.

Schedule your consultation today to understand the BMT process, donor options, treatment costs, and recovery plan, whether you are in India or travelling from abroad.